While this isn’t specifically game related, Cathy Moore is one of my favourite eLearning gurus – she always provides highly practical and very useful suggestions for designing more accessible and eLearning content with a heavy learner focus. This Slideshare presentation encapsulates the heart of her message.
http://www.slideshare.net/mobile/CathyMoore/dump-the-drone-easy-steps-to-livelier-elearning